Yes. Because the ETravelSim Vatican City eSIM rides on Vodafone Italia's network, it works across Rome (the Colosseum, Trastevere, Termini station, Fiumicino and Ciampino airports) and the rest of Italy on the same plan. This is useful because most Vatican visitors spend less than half a day inside Vatican territory and the rest of their trip in Rome or other Italian cities. Expect signal at the Pantheon, Piazza Navona, Florence's Duomo, Venice's Grand Canal, and Naples on the same eSIM.